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USM研究者的设备旨在防止呼吸机呼吸并发症 in COVID-19, ICU and Surgery Patients

Tue, 06/30/2020 - 19:15pm | By: Kendra Ablaza

Researcher tests the Oral Suction Device, a sponge-like insert for the back of the throat机械通气是抢救治疗,但它也可以引进并发症 医院患者的治疗计划。唾液可能在气管内池 管连接到患者的换气装置中,这可能导致许多问题,包括 bacterial infections and pneumonia.

Dr. Nina Mclain博士。尼娜·麦克莱恩,护士麻醉计划协调员和内副教授 护理和保健行业的南密西西比的大学的大学, 设计了口腔抽吸装置,海绵状插入了喉咙的后部 能够降低或防止病毒或细菌感染及相关疾病 for patients on ventilators. This can mean relief for several million surgery and ICU patients each year, Mclain said.

麦克莱恩和她的团队也在寻找到设备的潜在分配抗生素 or anti-viral medication to patients during treatment. This could be instrumental in special cases such as complications from COVID-19.

麦克莱恩赢得了她的学士学位从USM,她的硕士从泽维尔大学 在新奥尔良,她的博士来自弗吉尼亚联邦大学。她教 和做临床工作在桑福德大学的时候,她想出了一个主意,她 device in 2013.

而作为一名护士麻醉师工作,麦克莱恩多次发现呼吸系统并发症 在昏迷和气管插管患者呼吸机是由收购呼吸机相关 pneumonia more likely.

在当时存在的解决方案,从理想远。大约每30分钟 一个小时后,护士会用抽吸导管去除分泌物。其他类型 of suction were available but still didn’t solve the risk for infection.

“Every time they introduce that suction catheter, they are causing microtrauma in 口腔和咽喉,这也打开了其他途径感染,”麦克莱恩说。

Researcher tests the device她的设备是一个海绵包裹在凝胶和在喉部的后面插入。它 防止分泌物由于设备集中,使吸“持续可用。” Mclain said. The device can also be changed every 24 to 72 hours.

“Right now, there’s nothing else like this on the market,” Mclain said.

起初,她开始对产品的设计和她的研究伙伴博士工作。 Jep Cole, a facial plastic surgeon and graduate of USM based in Flowood.

“He really helped me tweak it and enhance the coating,” Mclain said. “Once it got developed and we got the patent, he moved on to other projects.”

首先,他们必须开发一个原型,并在头部模型进行测试,以确保使它 正确地发挥作用,但它不是直到麦克莱恩到达USM的设备将 really take shape.

在2017年,当USM是需要一个护士麻醉计划协调员,MCLAIN返回 to her alma mater to take the position, as well as mentor, teach, and conduct her nursing research while maintaining her clinical skills.

麦克莱恩也很高兴能与她在她收到了她的设备支持 arrival to the University.

“The USM Research Foundation had a huge impact on me being able to move forward,” 麦克莱恩说。 “这不仅是他们的鼓励,但我也遇到了自己的板 and discussed it with them. They showed enthusiasm for the device, and that I was bringing it to USM.”

约翰尼阿瑟顿,董事基金会的董事会主席说,基金会 was excited and proud to be part of McLain’s journey and future of her device.

“这正是研究的基础上成立的理由,”阿瑟顿说。 “它 让我们能够支持我们的设施,工作人员和学生,因为他们拿出技术 and ideas that we think are market worthy.”

Her earliest financial support came from the USM Office of Technology Development Gap Fund. Sponsored by the Mississippi Defense Initiative, the fund is awarded to 进一步早期军用和民用技术的商业潜力 或创新。获奖者颁发了可用于工作“创新券” with USM or USM-approved vendors.

麦克莱恩用她的奖工作密西西比聚合物研究所,工业 高分子科学与工程USM的学校外展服务,提供广泛的 技术和科学资源。在一起时,它们确定了biofriendly聚合物 for the device’s gel coating that would not only create suction and absorb fluid, 但也容易产生。该团队还致力于研究如何浸渍设备的 gel coating with anti-viral or anti-bacterial medications.

Dr. Monica Tisack博士。莫妮卡tisack,该研究所的主任说,合作是理想的感谢 该研究所的涂料和医疗聚合物经验的专业知识。 MPI的 技术团队主管丽莎·肯普,技术服务代表caitlyne雪莉,以及 前者USM本科高分子专业的学生雅各布·麦克尼斯和PRINE纳撒尼尔 all helped develop the device’s manufacturing process.

“We were bringing in a skillset we were already very strong in,” Tisack said.

Mclain in August 2018 obtained U.S. and international patents for the device. Now 在第五代原型机,麦克莱恩一直专注于实验室研究,并会介绍 the device to market users for feedback soon, Tisack said.

“这个项目已具有挑战性,但我不会说这是不寻常的产品 发展” tisack说。 “每次迭代或下一个步骤通常带来材料 的变化,可能是也可能不是故意的。材料的方式彼此交互 需要你去适应,重新评估和重新优化。在产品开发周期反复 是很常见的;我们只是荣幸能够参与这样一个有利的发展 product.”

而tisack估计医疗器械产品的开发可以采取二至五年 多年来,麦克莱恩说与USM合作伙伴合作一直非常有助于获得 the device to potential customers.

例如,上升创意,一个USM艺术和设计方案下属,学生经营的图形 设计工作室,还在开发一种标识为麦克莱恩的公司生产的设备。

“我已经愿意处于刚吹走和努力,他们会去 to help you further your product or your idea,” Mclain said.

麦克莱恩说,她的目标是拥有一个大型医疗器械公司购买和农产品 the device, or for her team to manufacture the device themselves and create jobs.

“如果它可以把只有一个情况下呼吸机相关性肺炎或感染所致 to pooling secretions, then you’ve saved anywhere between $45,000 and $95,000 for 一个案件​​来对待,”麦克莱恩说。 “我们会预见到你想用这个 in every long-term ventilated patient or ICU-ventilated patient.”

tisack说,她希望工作,对设备进行一次的第六代原型 他们得到来自市场的反馈。因为麦克莱恩想出了这个主意,而她 treating patients, Tisack is confident her innovation will pay off.

“她看到与现有的产品和程序问题,并说必须有 一个更好的办法,” tisack说。 “在我看来,这是产生创新的最佳途径 new products. It is rewarding to work with such highly-applied people that create new solutions to solve today’s problems.”